Jigang Fan

Delineating the activation mechanism and conformational landscape of a class B G protein-coupled receptor glucagon receptor

Ying Wang, Mingyu Li, Wenqi Liang et al. · Computational and Structural Biotechnology Journal · 2022 · 56 citations · Full text

Markov State Models and Molecular Dynamics Simulations Reveal the Conformational Transition of the Intrinsically Disordered Hypervariable Region of K-Ras4B to the Ordered Conformation

Hao Zhang, Duan Ni, Jigang Fan et al. · Journal of Chemical Information and Modeling · 2022 · 34 citations

Mechanistic Insights into the Long-range Allosteric Regulation of KRAS Via Neurofibromatosis Type 1 (NF1) Scaffold Upon SPRED1 Loading

Min-Yu Li, Yuanhao Wang, Jigang Fan et al. · Journal of Molecular Biology · 2022 · 30 citations

Neuroregeneration, Signal Transduction, Long-range Allosteric Regulation +11

Mechanistic insights into the clinical Y96D mutation with acquired resistance to AMG510 in the KRASG12C

Haiming Zhuang, Jigang Fan, Mingyu Li et al. · Frontiers in Oncology · 2022 · 16 citations · Full text

Elucidation of the conformational dynamics and assembly of Argonaute–RNA complexes by distinct yet coordinated actions of the supplementary microRNA

Haiming Zhuang, Xiaohua Fan, Dong Ji et al. · Computational and Structural Biotechnology Journal · 2022 · 14 citations · Full text