Mitochondria metabolism sets the species-specific tempo of neuronal development

Ryohei Iwata, Pierre Casimir, Emir Erkol, +24

Science

Brain DevelopmentMitochondria MetabolismNeuronal DevelopmentOxidative StressHuman Brain Development +15

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

Bruno Vasconcelos, Ilie‐Cosmin Stancu, Arjan Buist, +10

Acta Neuropathologica

Nonsense Mediated Decay Resistant Mutations Are a Source of Expressed Mutant Proteins in Colon Cancer Cell Lines with Microsatellite Instability

David S. Williams, Matthew Bird, Robert N. Jorissen, +5

PLoS ONE

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines

Ruben Boon, Manoj Kumar, Tine Tricot, +25

Nature Communications

In Vitro and In Vivo Evaluation of Cysteine Rebridged Trastuzumab–MMAE Antibody Drug Conjugates with Defined Drug-to-Antibody Ratios

Penny Bryant, Martin Pabst, George Badescu, +23

Molecular Pharmaceutics

ImmunologyPharmacotherapyDar 4ImmunotherapyStable Conjugate +14

MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway

Bilal N. Sheikh, Belinda Phipson, Farrah El-Saafin, +8

Oncogene

Signaling PathwayCell RegulationInk4a-arf PathwayCellular SenescenceCell Biology

Inhibition of glutamine synthetase in monocytes from patients with acute-on-chronic liver failure resuscitates their antibacterial and inflammatory capacity

Hannelie Korf, Johannie du Plessis, Jos van Pelt, +18

Gut

Site-Specific PEGylation at Histidine Tags

Yuehua Cong, Estera Pawlisz, Penny Bryant, +24

Bioconjugate Chemistry

The Metabolic Map into the Pathomechanism and Treatment of PGM1-CDG

Silvia Radenkovic, Matthew Bird, Tim L. Emmerzaal, +22

The American Journal of Human Genetics

Energy MetabolismSignal TransductionG Protein-coupled ReceptorCell SignalingPhysiology +11

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology

Sabrina Contino, Paolo E. Porporato, Matthew Bird, +9

Frontiers in Physiology