Larisza Gémesi

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

István Gyertyán, Béla Kiss, Katalin Sághy et al. · Neurochemistry International · 2011 · 144 citations

D3 Receptors, Psychiatry, Medicine +8

Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors

Éva Ágai-Csongor, György Domány, Katalin Nógrádi et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 89 citations · Full text

Medicinal Chemistry, Dopamine D3/d2 Receptors, Psychoactive Drug +8

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

István Gyertyán, Katalin Sághy, Judit Laszy et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2008 · 55 citations

Behavioral Sciences, Psychiatry, Behavioral Neuroscience +15

Effects of RGH-237 [N-{4-[4-(3-Aminocarbonyl-phenyl)-piperazin-1-yl]-butyl}-4-bromo-benzamide], an Orally Active, Selective Dopamine D3 Receptor Partial Agonist in Animal Models of Cocaine Abuse

István Gyertyán, Béla Kiss, Krisztina Gál et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 33 citations

Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile

Éva Ágai-Csongor, Katalin Nógrádi, János Galambos et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 21 citations · Full text

Psychiatry, Medicine, Eps Profile +11