Clinton D. Orebaugh

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

Anders R. Clausen, Scott A. Lujan, Adam Burkholder et al. · Nature Structural & Molecular Biology · 2015 · 196 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Dominant Mutations of the TREX1 Exonuclease Gene in Lupus and Aicardi-Goutières Syndrome

Jason M. Fye, Clinton D. Orebaugh, Stephanie R. Coffin et al. · Journal of Biological Chemistry · 2011 · 78 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

The TREX1 Exonuclease R114H Mutation in Aicardi-Goutières Syndrome and Lupus Reveals Dimeric Structure Requirements for DNA Degradation Activity

Clinton D. Orebaugh, Jason M. Fye, Scott Harvey et al. · Journal of Biological Chemistry · 2011 · 46 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

The TREX1 C-terminal Region Controls Cellular Localization through Ubiquitination

Clinton D. Orebaugh, Jason M. Fye, Scott Harvey et al. · Journal of Biological Chemistry · 2013 · 45 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +4

The Arg-62 Residues of the TREX1 Exonuclease Act Across the Dimer Interface Contributing to Catalysis in the Opposing Protomers

Jason M. Fye, Stephanie R. Coffin, Clinton D. Orebaugh et al. · Journal of Biological Chemistry · 2014 · 16 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14