Genomic atlas of the human plasma proteome

Benjamin B. Sun, Joseph Maranville, James E. Peters, +30

Nature

BioinformaticsProteomic TechnologyFunctional GenomicsMedicineProteasome +4

Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System

Erik S. Zimmerman, Tyler H. Heibeck, Avinash Gill, +16

Bioconjugate Chemistry

Peptide ScienceImmunotherapeuticsResultant AdcsImmunotherapySynthetic Immunology +21

Structural Basis for Assembly and Activation of the Heterotetrameric SAGA Histone H2B Deubiquitinase Module

Alwin Köhler, Erik S. Zimmerman, Maren Schneider, +2

Cell

ChromatinChromatin StructureBiochemistryChromatin RemodelingNatural Sciences +8

HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system

Jason L. DeHart, Erik S. Zimmerman, Orly Ardon, +3

Virology Journal

HIV-1 Vpr Triggers Natural Killer Cell–Mediated Lysis of Infected Cells through Activation of the ATR-Mediated DNA Damage Response

Jeffrey P. Ward, Zachary Davis, Jason L. DeHart, +6

PLoS Pathogens

Human Immunodeficiency Virus Type 1 Vpr-Mediated G₂ Arrest Requires Rad17 and Hus1 and Induces Nuclear BRCA1 and γ-H2AX Focus Formation

Erik S. Zimmerman, Junjie Chen, Joshua L. Andersen, +7

Molecular and Cellular Biology

Viral ReplicationImmunodeficienciesImmunologyCell DeathCell Cycle +15

HIV-1 Vpr-Induced Apoptosis Is Cell Cycle Dependent and Requires Bax but Not ANT

Joshua L. Andersen, Jason L. DeHart, Erik S. Zimmerman, +5

PLoS Pathogens

Human Immunodeficiency Virus Type 1 Vpr Induces DNA Replication Stress InVitro and In Vivo

Erik S. Zimmerman, Michael P. Sherman, Jana Blackett, +12

Journal of Virology

Activation of the ATR Pathway by Human Immunodeficiency Virus Type 1 Vpr Involves Its Direct Binding to Chromatin In Vivo

Maoyi Lai, Erik S. Zimmerman, Vicente Planelles, +1

Journal of Virology

Viral ReplicationImmunologyMolecular BiologyHiv-1 VprNormal Dna Replication +14

ATR and GADD45α mediate HIV-1 Vpr-induced apoptosis

Joshua L. Andersen, Erik S. Zimmerman, Jason L. DeHart, +5

Cell Death and Differentiation

MedicineHuman RetrovirusApoptosisImmunologyAntiviral Response +5