Siva Karthik Varanasi

Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors

Shihao Xu, Omkar Chaudhary, Patricia Rodríguez-Morales et al. · Immunity · 2021 · 673 citations · Full text

Cancer Immunosurveillance, Lipid Peroxidation, Immunology +9

Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

Michal Harel, Rona Ortenberg, Siva Karthik Varanasi et al. · Cell · 2019 · 325 citations · Full text

Medicine, Melanoma, Immunology +5

Manipulating mitochondrial electron flow enhances tumor immunogenicity

Kailash Chandra Mangalhara, Siva Karthik Varanasi, Melissa Johnson et al. · Science · 2023 · 105 citations · Full text

Radiation Oncology, Cancer Immunosurveillance, Mitochondrial Function +13

CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma

Dan Chen, Siva Karthik Varanasi, Toshiro Hara et al. · Immunity · 2023 · 98 citations · Full text

Neuro-oncology, Microglia Phagocytosis, Cancer Immunosurveillance +13

Bile acid synthesis impedes tumor-specific T cell responses during liver cancer

Siva Karthik Varanasi, Dan Chen, Yingluo Liu et al. · Science · 2025 · 95 citations · Full text