John Xi Chen

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

Heng Du, Lan Guo, Fang Fang et al. · Nature Medicine · 2008 · 932 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Receptor for Advanced Glycation End Product-Dependent Activation of p38 Mitogen-Activated Protein Kinase Contributes to Amyloid-β-Mediated Cortical Synaptic Dysfunction

Nicola Origlia, Massimo Righi, Simona Capsoni et al. · Journal of Neuroscience · 2008 · 199 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Inhibition of Amyloid-β (Aβ) Peptide-Binding Alcohol Dehydrogenase-Aβ Interaction Reduces Aβ Accumulation and Improves Mitochondrial Function in a Mouse Model of Alzheimer's Disease

Jun Yao, Heng Du, Shiqiang Yan et al. · Journal of Neuroscience · 2011 · 181 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell

Xueqi Gan, Shengbin Huang, Long Wu et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2013 · 181 citations · Full text

Life Sciences, Cell Biology, Neuroscience +15

Cyclophilin D Deficiency Rescues Axonal Mitochondrial Transport in Alzheimer’s Neurons

Lan Guo, Heng Du, Shiqiang Yan et al. · PLoS ONE · 2013 · 119 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17