Concepedia

Author

Edith L. Pfister

University of Massachusetts Chan Medical SchoolORCID

Also Known As

E Pfister, Edith L Pfister, Edith L. Pfister, Edith Pfister, Pfister, Edith L.

27

Publications

950

Citations

13

H-Index

19

Concepts

All Affiliations

University of Massachusetts Chan Medical SchoolMassachusetts General HospitalMaineGeneral Medical CenterHarvard UniversityUniversity College London
EL

About

Edith L. Pfister is an author at University of Massachusetts Chan Medical School specializing in genome editing, gene expression, and medicine.

Top Concepts

#ConceptH-IndexPublicationsCitations

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Medicine

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Engineering

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Natural Sciences

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Biochemistry

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Chemical Biology

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Edith L. Pfister

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13

Publications

887

Citations

12

H-Index

YearCitations

Five siRNAs Targeting Three SNPs May Provide Therapy for Three-Quarters of Huntington's Disease Patients

Edith L. Pfister, Lori Kennington, Juerg Straubhaar,

Current Biology

2009

248

HTT-lowering reverses Huntington’s disease immune dysfunction caused by NFκB pathway dysregulation

Ulrike Träger, Ralph André, Nayana Lahiri,

Brain

2014

178

Epidemiologic Study of Abuse of Analgesics Containing Phenacetin

U. C. Dubach, Bernard Rosner, Edith L. Pfister

New England Journal of Medicine

1983

138

Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease

Edith L. Pfister, Natalie DiNardo, Erica Mondo,

Human Gene Therapy

2017

86

Alterations in mRNA 3′ UTR Isoform Abundance Accompany Gene Expression Changes in Human Huntington’s Disease Brains

Lindsay Romo, Ami Ashar-Patel, Edith L. Pfister,

Cell Reports

2017

46

Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington’s disease models

Faith Conroy, Rachael Miller, Julia F. Alterman,

Nature Communications

2022

46

Cellular Analysis of Silencing the Huntington’s Disease Gene Using AAV9 Mediated Delivery of Artificial Micro RNA into the Striatum of Q140/Q140 Mice

Allison M. Keeler, Ellen Sapp, Kathryn Chase,

Journal of Huntington s Disease

2016

35

Safe and Efficient Silencing with a Pol II, but Not a Pol lII, Promoter Expressing an Artificial miRNA Targeting Human Huntingtin

Edith L. Pfister, Kathryn Chase, Huaming Sun,

Molecular Therapy — Nucleic Acids

2017

28

Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells

James R. C. Miller, Edith L. Pfister, Wanzhao Liu,

Scientific Reports

2017

24

Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity

Ken Yamada, Samuel Hildebrand, Sarah M. Davis,

Nucleic Acids Research

2021

20

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