Kenneth J. Wiggall

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

Ujunwa Cynthia Okoye-Okafor, Boris Bartholdy, Jessy Cartier et al. · Nature Chemical Biology · 2015 · 174 citations · Full text

Hematological Malignancy, Medicine, Acute Myeloid Leukemia +8

3-(1,1-Dioxo-2<i>H</i>-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1<i>H</i>)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase

Rosanna Tedesco, Antony N. Shaw, Ramesh Bambal et al. · Journal of Medicinal Chemistry · 2006 · 159 citations · Full text

Hydrazinonaphthalene and Azonaphthalene Thrombopoietin Mimics Are Nonpeptidyl Promoters of Megakaryocytopoiesis

Kevin J. Duffy, Michael G. Darcy, Evelyne Delorme et al. · Journal of Medicinal Chemistry · 2001 · 119 citations · Full text

Drug Target, Molecular Biology, Pharmacotherapy +17

Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 1. Discovery and Optimization of Salicylaldehyde Thiosemicarbazone Thrombopoietin Mimics

Kevin J. Duffy, Anthony N. Shaw, Evelyne Delorme et al. · Journal of Medicinal Chemistry · 2002 · 87 citations

Pharmaceutical Research, Bioorganic Chemistry, Pharmacotherapy +18

Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 2. Rational Design of Naphtho[1,2-<i>d</i>]imidazole Thrombopoietin Mimics

Kevin J. Duffy, Alan T. Price, Evelyne Delorme et al. · Journal of Medicinal Chemistry · 2002 · 59 citations