The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

Seokmann Hong, Michael T. Wilson, Isao Serizawa, +10

Nature Medicine

Diabetes ManagementAutoimmune DiseaseNon-obese Diabetic MiceMedicineDiabetes +8

Cutting edge: activation of NK T cells by CD1d and alpha-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype.

Nagendra Singh, Seokmann Hong, David C. Scherer, +5

PubMed

ImmunologyImmune RegulationImmunologic MechanismCd4 T Cell ResponsesImmunotherapy +14

Cutting Edge: Activation of NK T Cells by CD1d and α-Galactosylceramide Directs Conventional T Cells to the Acquisition of a Th2 Phenotype

Nagendra Singh, Seokmann Hong, David C. Scherer, +5

The Journal of Immunology

Adaptive Immune SystemImmune RegulationImmunologyImmunologic MechanismCd4 T Cell Responses +18

An Essential Role of Mast Cells in the Development of Airway Hyperresponsiveness in a Murine Asthma Model

Tetsuto Kobayashi, Toru Miura, Tomoko Haba, +4

The Journal of Immunology

AsthmaInflammatory Lung DiseaseLung InflammationMast Cell DisorderImmunology +17

CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells

Tomoko Watanabe, Jun‐Ichi Masuyama, Yoshiaki Sohma, +11

Clinical Immunology

Novel Costimulatory MoleculeSignal TransductionT-regulatory CellImmunologyImmunologic Mechanism +6

Quantitative and Qualitative Differences in the In Vivo Response of NKT Cells to Distinct α- and β-Anomeric Glycolipids

Vrajesh V. Parekh, Avneesh K. Singh, Michael T. Wilson, +10

The Journal of Immunology

Germinated barley foodstuff, a prebiotic product, ameliorates inflammation of colitis through modulation of the enteric environment

Osamu Kanauchi, Isao Serizawa, Yoshio Araki, +8

Journal of Gastroenterology

Chronic Inflammatory DiseasesDysbiosisImmunologyGastroenterologyProbiotics +15

Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia

Nakayuki Honma, Haruhiko Koseki, Takeshi Akasaka, +6

Immunology

Mouse Strain DeficientMif GeneImmunologyImmune RegulationPathology +22

Antitumor Activity of α-Galactosylceramide, KRN7000, in Mice With the Melanoma B16 Hepatic Metastasis and Immunohistological Study of Tumor Infiltrating Cells

Ryusuke Nakagawa, Isao Serizawa, Kazuhiro Motoki, +6

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics

Antitumor ActivityImmunologyNk CellsPathologyCell Death +20

Roles of mitogen-activated protein kinase pathways for mediator release from human cultured mast cells

Masahiro Kimata, Naoki Inagaki, Toshinobu Kato, +3

Biochemical Pharmacology

Developmental BiologySignal TransductionSignaling PathwayCell RegulationReceptor Tyrosine Kinase +8