Assessment of post‐mortem‐induced changes to the mouse brain proteome

Stephen W. Hunsucker, Benjamin Solomon, Jeremy W. Gawryluk, +4

Journal of Neurochemistry

Methylation-mediated downregulation of the B-cell translocation gene 3 (BTG3) in breast cancer cells.

Jingwei Yu, Yingsha Zhang, Zhongxia Qi, +3

PubMed

Breast OncologyEpigenetic ChangeCancer BiologyEpigeneticsTumor Biology +18

Brain Phenotype of Transgenic Mice Overexpressing Cystathionine β-Synthase

Vinciane Régnier, Jean‐Marie Billard, Sapna Gupta, +13

PLoS ONE

Reduced purine biosynthesis in humans after their divergence from Neandertals

Vita V. Stepanova, Kaja Ewa Moczulska, Guido N. Vacano, +23

eLife

GeneticsMetabolomic ProfilingAmino Acid SubstitutionAmino Acid MetabolismBiosynthesis +17

APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer’s cases

Paula Perez‐Corredor, Timothy E. Vanderleest, Guido N. Vacano, +13

Frontiers in Molecular Neuroscience

The Use of Mouse Models for Understanding the Biology of Down Syndrome and Aging

Guido N. Vacano, Nathan Duval, David Patterson

Current Gerontology and Geriatrics Research

CytogeneticsGeneticsBiogerontologyEpigeneticsMouse Models +16

The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation

Randall C. Mazzarino, Veronika Barešová, Marie Zikánová, +4

Molecular Genetics and Metabolism Reports

Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: Cellular models of de novo purine biosynthesis deficiency disorders

Nathan Duval, Kyleen Luhrs, Terry G. Wilkinson, +6

Molecular Genetics and Metabolism

Adrenal GlandBiosynthesisAdei MutantsCellular EnzymologyBiochemistry +10

Rapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging

Nathan Duval, Guido N. Vacano, David Patterson

Frontiers in Aging Neuroscience

AgingTs65dn Mouse ModelNeurochemical BiomarkersBiogerontologyAlzheimer's Disease +15

Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells

Jaime F. Modiano, Juan Sun, Julie Lang, +8

Clinical Immunology

Activated T CellsAutoimmune DiseaseT-regulatory CellImmunologyFas Ligand-dependent Suppression +9