Production of pancreatic hormone–expressing endocrine cells from human embryonic stem cells

Kevin A. D’Amour, Anne G. Bang, Susan Eliazer, +7

Nature Biotechnology

Embryo CultureEndocrine CellsEmbryonic Stem CellInduced Pluripotent Stem CellDevelopmental Biology +7

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

Evert Kroon, Laura A. Martinson, Kuniko Kadoya, +11

Nature Biotechnology

Regenerative MedicineInduced Pluripotent Stem CellDevelopmental BiologyPancreatic EndodermGlucose-responsive Insulin-secreting Cells +6

Efficient differentiation of human embryonic stem cells to definitive endoderm

Kevin A. D’Amour, Alan D. Agulnick, Susan Eliazer, +3

Nature Biotechnology

Embryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyCell SpecializationMedicine +8

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

Evert Kroon

The EMBO Journal

Bone Marrow FailureCell DivisionHoxa9 TransformsMedicineStem Cell Mobilization +8

A Scalable System for Production of Functional Pancreatic Progenitors from Human Embryonic Stem Cells

Thomas C. Schulz, Holly Young, Alan D. Agulnick, +25

PLoS ONE

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

Olivia Kelly, Man Yin Chan, Laura A. Martinson, +10

Nature Biotechnology

Developmental BiologyPancreatic CancerCell SpecializationMedicineCell-surface Markers +5

Overexpression of the myeloid leukemia–associatedHoxa9 gene in bone marrow cells induces stem cell expansion

Unnur Þorsteinsdóttir, Aline Mamo, Evert Kroon, +5

Blood

In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein

Jana Krošl, Pamela Austin, Nathalie Beslu, +3

Nature Medicine

Cell TherapyVitro ExpansionDevelopmental BiologyMedicineStem Cell Mobilization +9

Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation device

A. M. James Shapiro, David Thompson, Thomas Donner, +11

Cell Reports Medicine

Tissue EngineeringEngineeringImmunologyPancreas TransplantationBiomedical Engineering +16

Defining Roles for <i>HOX</i> and <i>MEIS1</i> Genes in Induction of Acute Myeloid Leukemia

Unnur Þorsteinsdóttir, Evert Kroon, Lori Jerome, +2

Molecular and Cellular Biology

Mixed-phenotype Acute LeukemiaGeneticsMolecular GeneticsEpigeneticsMyeloid Neoplasia +17