Concepedia

Author

Laurent Detalle

Ablynx (Belgium)ORCID

Also Known As

L Detalle, L. Detalle, LAURENT DETALLE, Laurent Detalle

28

Publications

1.1K

Citations

14

H-Index

10

Concepts

All Affiliations

Ablynx (Belgium)Baylor College of MedicineUCB Pharma (United Kingdom)Queen's University BelfastIowa State University
LD

About

Laurent Detalle is an author at Ablynx (Belgium) specializing in nanomanufacturing, engineering, and biomolecular engineering.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Engineering

1

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32

2

Medicine

1

2

246

3

Biomedical Engineering

1

1

32

4

Biomolecular Engineering

1

1

32

5

Nanomanufacturing

1

1

32

Laurent Detalle

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11

Publications

717

Citations

11

H-Index

YearCitations

Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

Laurent Detalle, Thomas Stöhr, Concepción Palomo,

Antimicrobial Agents and Chemotherapy

2015

289

Nebulised ALX-0171 for respiratory syncytial virus lower respiratory tract infection in hospitalised children: a double-blind, randomised, placebo-controlled, phase 2b trial

Steve Cunningham, Pedro A. Piedra, Federico Martinón‐Torres,

The Lancet Respiratory Medicine

2020

123

Delivery of ALX-0171 by inhalation greatly reduces respiratory syncytial virus disease in newborn lambs

Alejandro Larios Mora, Laurent Detalle, Jack M. Gallup,

mAbs

2018

95

Phase 1/1b Studies of <scp>UCB0599</scp>, an Oral Inhibitor of α‐Synuclein Misfolding, Including a Randomized Study in Parkinson's Disease

Johan W. Smit, Peter Basile, Maria Key Prato,

Movement Disorders

2022

51

Trivalency of a Nanobody Specific for the Human Respiratory Syncytial Virus Fusion Glycoprotein Drastically Enhances Virus Neutralization and Impacts Escape Mutant Selection

Concepción Palomo, Vicente Más, Laurent Detalle,

Antimicrobial Agents and Chemotherapy

2016

36

High Throughput Combinatorial Formatting of PcrV Nanobodies for Efficient Potency Improvement

Evelyn De Tavernier, Laurent Detalle, Erika Morizzo,

Journal of Biological Chemistry

2016

32

Kinetics of Respiratory Syncytial Virus (RSV) Memphis Strain 37 (M37) Infection in the Respiratory Tract of Newborn Lambs as an RSV Infection Model for Human Infants

Alejandro Larios Mora, Laurent Detalle, Albert Van Geelen,

PLoS ONE

2015

25

Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial

Elisabeth De Leeuw, Karel Van Damme, Jozefien Declercq,

Respiratory Research

2022

22

Comparative Therapeutic Potential of ALX-0171 and Palivizumab against Respiratory Syncytial Virus Clinical Isolate Infection of Well-Differentiated Primary Pediatric Bronchial Epithelial Cell Cultures

Lindsay Broadbent, Hong Guo-Parke, Lyndsey J. Ferguson,

Antimicrobial Agents and Chemotherapy

2019

19

Two‐Step Mechanism of Virus‐induced Autoimmune Hemolytic Anemia

Jean‐Paul Coutelier, Laurent Detalle, Andrei Musaji,

Annals of the New York Academy of Sciences

2007

14

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