Immune control of HIV-1 after early treatment of acute infection

Eric Rosenberg, Marcus Altfeld, Samuel Poon, +7

Nature

Primary ImmunodeficiencyHuman RetrovirusImmunologyAntiviral TherapyAntiviral Response +6

Comprehensive Epitope Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses Directed against the Entire Expressed HIV-1 Genome Demonstrate Broadly Directed Responses, but No Correlation to Viral Load

Marylyn M. Addo, Xu G. Yu, Almas Rathod, +17

Journal of Virology

T-regulatory CellImmunologyHiv-1 GenomeCd4 T Cell ResponsesImmunotherapy +17

Cellular Immune Responses and Viral Diversity in Individuals Treated during Acute and Early HIV-1 Infection

Marcus Altfeld, Eric Rosenberg, Raj Shankarappa, +15

The Journal of Experimental Medicine

Early Hiv-1 InfectionAcute Hiv InfectionImmunologyCd4 T Cell ResponsesImmune System +16

Selective Escape from CD8 ⁺ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution

Todd M. Allen, Marcus Altfeld, Shaun C. Geer, +19

Journal of Virology

Substantial Differences in Specificity of HIV-Specific Cytotoxic T Cells in Acute and Chronic HIV Infection

Philip Goulder, Marcus Altfeld, Eric Rosenberg, +12

The Journal of Experimental Medicine

Chronic Hiv InfectionT-regulatory CellImmunologyImmunodominanceInitial Ctl Response +16

The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals

Marylyn M. Addo, Marcus Altfeld, Eric Rosenberg, +9

Proceedings of the National Academy of Sciences

Hiv-1-infected IndividualsT-regulatory CellImmunologyImmune RegulationAntigen Processing +15

Vpr Is Preferentially Targeted by CTL During HIV-1 Infection

Marcus Altfeld, Marylyn M. Addo, Robert L. Eldridge, +12

The Journal of Immunology

Identification of Dominant Optimal HLA-B60- and HLA-B61-Restricted Cytotoxic T-Lymphocyte (CTL) Epitopes: Rapid Characterization of CTL Responses by Enzyme-Linked Immunospot Assay

Marcus Altfeld, Alicja Trocha, Robert L. Eldridge, +9

Journal of Virology

Identification of Novel HLA-A2-Restricted Human Immunodeficiency Virus Type 1-Specific Cytotoxic T-Lymphocyte Epitopes Predicted by the HLA-A2 Supertype Peptide-Binding Motif

Marcus Altfeld, Brian Livingston, Neha Reshamwala, +20

Journal of Virology

Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus

Rika Draenert, Todd M. Allen, Yang Liu, +11

The Journal of Experimental Medicine

Monozygotic Adult TwinsGeneticsImmunologyImmunodominanceCd4 T Cell Responses +18