Joseph E. Wedekind

The Enolase Superfamily:  A General Strategy for Enzyme-Catalyzed Abstraction of the α-Protons of Carboxylic Acids

Patricia C. Babbitt, Miriam S. Hasson, Joseph E. Wedekind et al. · Biochemistry · 1996 · 307 citations

Life Sciences, Biochemistry, Molecular Biology +12

Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance

Arun K. Ghosh, P. Sridhar, Sofiya Leshchenko et al. · Journal of Medicinal Chemistry · 2006 · 155 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Comparison of a PreQ1 Riboswitch Aptamer in Metabolite-bound and Free States with Implications for Gene Regulation

Jermaine L. Jenkins, J. Krucinska, Reid M. McCarty et al. · Journal of Biological Chemistry · 2011 · 140 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A Carboxylate Oxygen of the Substrate Bridges the Magnesium Ions at the Active Site of Enolase:  Structure of the Yeast Enzyme Complexed with the Equilibrium Mixture of 2-Phosphoglycerate and Phosphoenolpyruvate at 1.8 Å Resolution^,

Todd M. Larsen, Joseph E. Wedekind, Ivan Rayment et al. · Biochemistry · 1996 · 128 citations

Life Sciences, Biochemistry, Molecular Biology +15

Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity 1 1Edited by D. Rees

Joseph E. Wedekind, Christine B. Trame, Magdalena Dorywalska et al. · Journal of Molecular Biology · 2001 · 116 citations

Life Sciences, Biochemistry, Microbiology +10