Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation

Erez Dror, Élise Dalmas, Daniel T. Meier, +17

Nature Immunology

InflammationMetabolic SyndromeCytokineInsulin SignalingInsulin Management +10

Mesenteric Fat Lipolysis Mediates Obesity-Associated Hepatic Steatosis and Insulin Resistance

Stephan Wueest, Flurin Item, Fabrizio C. Lucchini, +4

Diabetes

Electric Pulse Stimulation of Cultured Murine Muscle Cells Reproduces Gene Expression Changes of Trained Mouse Muscle

Nathalie Burch, Anne‐Sophie Arnold, Flurin Item, +6

PLoS ONE

Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance

Michael Wiedemann, Stephan Wueest, Flurin Item, +2

American Journal of Physiology-Endocrinology and Metabolism

Metabolic DisorderImmunologyPathologyFatty Liver DiseaseGlucose Tolerance +20

Induction of Cytosolic Phospholipase A2α Is Required for Adipose Neutrophil Infiltration and Hepatic Insulin Resistance Early in the Course of High-Fat Feeding

Nurit Hadad, Olga Burgazliev, Vered Elgazar-Carmon, +6

Diabetes

ImmunologyPathologyFatty Liver DiseaseInsulin SignalingInflammation +20

Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice

Stephan Wueest, Flurin Item, Christina N. Boyle, +10

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

ImmunologyFastingEarly FastingInflammationMetabolic Syndrome +17

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

Flurin Item, Stephan Wueest, Vera Lemos, +14

Nature Communications

ASK1 inhibits browning of white adipose tissue in obesity

Fabrizio C. Lucchini, Stephan Wueest, Tenagne D. Challa, +7

Nature Communications

IL-6–Type Cytokine Signaling in Adipocytes Induces Intestinal GLP-1 Secretion

Stephan Wueest, Céline Isabelle Laesser, Marianne Böni‐Schnetzler, +6

Diabetes

Real-World Use of Oral Semaglutide in Adults with Type 2 Diabetes: The PIONEER REAL Switzerland Multicentre, Prospective, Observational Study

Anastas Kick, Khadija M'Rabet‐Bensalah, Flavio Acquistapace, +7

Diabetes Therapy