Ian A. Baines

The Phosphorylation of Eukaryotic Initiation Factor eIF4E in Response to Phorbol Esters, Cell Stresses, and Cytokines Is Mediated by Distinct MAP Kinase Pathways

Xuemin Wang, Andrea Flynn, Andrew J. Waskiewicz et al. · Journal of Biological Chemistry · 1998 · 301 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Preclinical Strategy to Reduce Clinical Hepatotoxicity Using in Vitro Bioactivation Data for >200 Compounds

Melanie Z. Sakatis, Melinda J. Reese, Andrew W. Harrell et al. · Chemical Research in Toxicology · 2012 · 121 citations

Pharmacy, Pharmacology, Toxicology +17

An integrated reactive metabolite evaluation approach to assess and reduce safety risk during drug discovery and development

Melinda J. Reese, Melanie Z. Sakatis, Jeffrey L. Ambroso et al. · Chemico-Biological Interactions · 2010 · 29 citations

Pharmacy, Pharmacology, Toxicology +16

The Drosophila cell shape regulator c-Jun N-terminal kinase also functions as a stress-activated protein kinase

J Botella, Ian A. Baines, Daniel Williams et al. · Insect Biochemistry and Molecular Biology · 2001 · 21 citations

Life Sciences, Cell Biology, Molecular Biology +9

Use of human tissue in ADME and safety profiling of development candidates

Robert A. Coleman, Wayne P. Bowen, Ian A. Baines et al. · Drug Discovery Today · 2001 · 14 citations

Pharmacy, Toxicology, Tissue Engineering +6