Alexandre J. Buckmelter

Molecular basis of USP7 inhibition by selective small-molecule inhibitors

A.P. Turnbull, Stephanos Ioannidis, Wojciech Krajewski et al. · Nature · 2017 · 448 citations

Drug Target, Usp7 Inhibition, Medicine +4

USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylation

Emma V. Rusilowicz-Jones, Jane Jardine, Andreas Kallinos et al. · Life Science Alliance · 2020 · 124 citations · Full text

Mitophagy, Trigger Threshold, Molecular Biology +19

Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors

Xiaozhang Zheng, Paul Bauer, Timm Baumeister et al. · Journal of Medicinal Chemistry · 2013 · 80 citations · Full text

Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors

Xiaozhang Zheng, Paul Bauer, Timm Baumeister et al. · Journal of Medicinal Chemistry · 2013 · 68 citations · Full text

Drug Target, Biomolecular Structure Prediction, Pharmacotherapy +23

Conformational Memory in Enantioselective Radical Reductions and a New Radical Clock Reaction

Alexandre J. Buckmelter, Angie I. Kim, Scott D. Rychnovsky · Journal of the American Chemical Society · 2000 · 52 citations