Kelsie L. Thu

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Hong Xu, Marco Di Antonio, Steven McKinney et al. · Nature Communications · 2017 · 588 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells

Kazuhiko Shien, Shinichi Toyooka, Hiromasa Yamamoto et al. · Cancer Research · 2013 · 273 citations · Full text

Medicine, Oncology, Pharmacology +17

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2

Satoshi Inoue, Wanda Y. Li, Alan Tseng et al. · Cancer Cell · 2016 · 198 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

Victor D. Martínez, Emily A. Vucic, Kelsie L. Thu et al. · Scientific Reports · 2015 · 167 citations · Full text

Medicine, Molecular Biology, Oncology +15

DNA Methylation Is Globally Disrupted and Associated with Expression Changes in Chronic Obstructive Pulmonary Disease Small Airways

Emily A. Vucic, Raj Chari, Kelsie L. Thu et al. · American Journal of Respiratory Cell and Molecular Biology · 2013 · 156 citations · Full text

Medicine, Genetics, Molecular Biology +17