Robert Meinecke

Direct Observation of Ligand Binding to Membrane Proteins in Living Cells by a Saturation Transfer Double Difference (STDD) NMR Spectroscopy Method Shows a Significantly Higher Affinity of Integrin α_IIbβ₃ in Native Platelets than in Liposomes

Birgit Claasen, Marco Axmann, Robert Meinecke et al. · Journal of the American Chemical Society · 2004 · 201 citations

Life Sciences, Biochemistry, Biophysics +17

Detecting Binding Affinity to Immobilized Receptor Proteins in Compound Libraries by HR-MAS STD NMR

Jens Klein, Robert Meinecke, Moriz Mayer et al. · Journal of the American Chemical Society · 1999 · 185 citations

Pharmacy, Medicinal Chemistry, Drug Discovery +13

Determination of the Binding Specificity of an Integral Membrane Protein by Saturation Transfer Difference NMR:  RGD Peptide Ligands Binding to Integrin α_IIbβ₃

Robert Meinecke, Bernd Meyer · Journal of Medicinal Chemistry · 2001 · 122 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists

J. Schiebel, Nedyalka Radeva, Helene Köster et al. · ChemMedChem · 2015 · 69 citations

Pharmacy, Biochemistry, Medicinal Chemistry +17

A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I

Rebecca Ebenhoch, Simone Prinz, Susann Kaltwasser et al. · Proceedings of the National Academy of Sciences · 2020 · 17 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17