Leigh Wellhauser

High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons

Prasad S. Dalvi, Jennifer A. Chalmers, Vicky Luo et al. · International Journal of Obesity · 2016 · 225 citations · Full text

Life Sciences, Neuroscience, Physiology +17

Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons

Leigh Wellhauser, Denise D. Belsham · Journal of Neuroinflammation · 2014 · 108 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue

Steven V. Molinski, Saumel Ahmadi, Wan Ip et al. · EMBO Molecular Medicine · 2017 · 105 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia

Saumel Ahmadi, Zoltán Bozóky, Michelle Di Paola et al. · npj Genomic Medicine · 2017 · 89 citations · Full text

Medicine, Molecular Medicine, Pharmacology +15

A Small-Molecule Modulator Interacts Directly with ΔPhe508-CFTR to Modify Its ATPase Activity and Conformational Stability

Leigh Wellhauser, Patrick Kim Chiaw, Stan Pasyk et al. · Molecular Pharmacology · 2009 · 70 citations

Life Sciences, Biochemistry, Molecular Biology +17