Concepedia

Joseph E. Deweese

JE

Statistics

Publications

22

Citations

970

H-Index

18

Active since

2008

Affiliations

Vanderbilt University(Current)

Lipscomb University

Tennessee Technological University

VA Tennessee Valley Healthcare System

Joseph E. Deweese is an author at Vanderbilt University specializing in topoisomerase ii function, topoisomerase activity, and dna cleavage.

ORCID

Publications per year

2008–2021

22

Publications

22

A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases

Bryan H. Thurtle-Schmidt, Alex B. Burgin, Joseph E. Deweese et al. · Nature · 2010 · 177 citations · Full text

, , +9

DNA topology and topoisomerases

Joseph E. Deweese, Michael A. Osheroff, Neil Osheroff · Biochemistry and Molecular Biology Education · 2009 · 128 citations · Full text

, , +13

DNA cleavage and opening reactions of human topoisomerase IIα are regulated <i>via</i> Mg <sup>2+</sup> -mediated dynamic bending of gate-DNA

Sang-Hwa Lee, Seung‐Ryoung Jung, Kang Heo et al. · Proceedings of the National Academy of Sciences · 2012 · 73 citations · Full text

, , +13

Human topoisomerase II  uses a two-metal-ion mechanism for DNA cleavage

Joseph E. Deweese, Alex B. Burgin, Neil Osheroff · Nucleic Acids Research · 2008 · 63 citations · Full text

, , +12

Etoposide Quinone Is a Redox-Dependent Topoisomerase II Poison

David Jacob, Susan L. Mercer, Neil Osheroff et al. · Biochemistry · 2011 · 55 citations

, , +15

1–5 of 22