Dorothy T. Steimel

Human cytochrome P450IIA3: cDNA sequence role of the enzyme in the metabolic of promutagens comparison to nitrosamine activation by human cytochrome P450IIE1

Charles L. Crespi, Bruce W. Penman, J Leakey et al. · Carcinogenesis · 1990 · 146 citations

A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing

Charles L. Crespi, Frank J. Gonzalez, Dorothy T. Steimel et al. · Chemical Research in Toxicology · 1991 · 141 citations

Chemoprevention Strategy, Linear Interpolation, Toxicological Mechanism +17

The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin B₁ and comparison to CYP1A2 and CYP2A3

Charles L. Crespi, Bruce W. Penman, Dorothy T. Steimel et al. · Carcinogenesis · 1991 · 140 citations

Development of a human lymphoblastoid cell line constitutively expressing human CYP1B1 cDNA: substrate specificity with model substrates and promutagens

Charles L. Crespi, B. W-Penman, Dorothy T. Steimel et al. · Mutagenesis · 1997 · 112 citations · Full text

Detection and characterization of novel polymorphisms in the CYP2E1 gene

Karen S. Fairbrother, Jane I. Grove, Isabelle de Waziers et al. · Pharmacogenetics · 1998 · 105 citations