A New Model of Cerebral Microthrombosis in Rats and the Neuroprotective Effect of a Rho-Kinase Inhibitor

Yoshinori Toshima, Shin’ichi Satoh, Ichiro Ikegaki, +1

Stroke

Wide therapeutic time window for Rho-kinase inhibition therapy in ischemic brain damage in a rat cerebral thrombosis model

Shin’ichi Satoh, Yoshinori Toshima, Asako Hitomi, +3

Brain Research

ThrombosisRho-kinase Inhibition TherapyIschemic StrokeStrokeMedicine +13

Development of the Olfactory Epithelium and Vomeronasal Organ in the Japanese Reddish Frog, Rana japonica.

K. Taniguchi, Yoshinori Toshima, Tôru Saitô, +1

Journal of Veterinary Medical Science

Demonstration of elevation and localization of Rho-kinase activity in the brain of a rat model of cerebral infarction

Kazuo Yano, Koh Kawasaki, Tsuyoshi Hattori, +7

European Journal of Pharmacology

Cerebral Vascular RegulationNeurophysiologyCellular NeuroscienceNeuroanatomyPhysiology +13

Antianginal effects of hydroxyfasudil, a Rho‐kinase inhibitor, in a canine model of effort angina

Tatsuma Utsunomiya, Shin’ichi Satoh, Ichiro Ikegaki, +3

British Journal of Pharmacology

Wide therapeutic time window for fasudil neuroprotection against ischemia-induced delayed neuronal death in gerbils

Shin’ichi Satoh, Yoshinori Toshima, Ichiro Ikegaki, +2

Brain Research

NeurophysiologyMedicineCell DeathNeuropharmacologySocial Sciences +10

Thromboxane A2 synthetase inhibitor failed to ameliorate the arterial narrowing during the chronic phase of cerebral vasospasm

Yoshinori Toshima, Shin’ichi Satoh, Ichiro Ikegaki, +3

Life Sciences

Chronic PhaseThrombosisVascular DiseaseCardiovascular DiseaseMedicine +13

Effect of dietary docosahexaenoic acid in the rat middle cerebral artery thrombosis model

Kazuo Umemura, Yoshinori Toshima, Fumitoshi Asai, +1

Thrombosis Research

ThrombosisCerebral Vascular RegulationOmega-3 Fatty AcidMedicinePhysiology +9

Fasudil, a protein kinase inhibitor, prevents the development of endothelial injury and neutrophil infiltration in a two-haemorrhage canine subarachnoid model

S. Satoh, Yasuhiro Yamamoto, Yoshinori Toshima, +4

Journal of Clinical Neuroscience

InflammationMedicinePhysiologyEndothelial DysfunctionPathology +7

Effects of Rho-kinase inhibitor on vasopressin-induced chronic myocardial damage in rats

Shin-ichi Satoh, Ichiro Ikegaki, Yoshinori Toshima, +3

Life Sciences

Cardiac MuscleCardiomyopathyHeart FailureCardiovascular DiseaseMedicine +8