Iván Plaza-Menacho

A Role for Glial Cell–Derived Neurotrophic Factor–Induced Expression by Inflammatory Cytokines and RET/GFRα1 Receptor Up-regulation in Breast Cancer

Selma Esseghir, Shawn Todd, Toby Hunt et al. · Cancer Research · 2007 · 148 citations · Full text

Medicine, Molecular Biology, Oncology +17

Targeting the receptor tyrosine kinase RET sensitizes breast cancer cells to tamoxifen treatment and reveals a role for RET in endocrine resistance

Iván Plaza-Menacho, Andrea Morandi, David Robertson et al. · Oncogene · 2010 · 143 citations

Medicine, Cancer Biology, Oncology +16

GDNF–RET Signaling in ER-Positive Breast Cancers Is a Key Determinant of Response and Resistance to Aromatase Inhibitors

Andrea Morandi, Lesley‐Ann Martin, Qiong Gao et al. · Cancer Research · 2013 · 118 citations

Medicine, Endocrinology, Cancer Pharmacology +16

Sorafenib Functions to Potently Suppress RET Tyrosine Kinase Activity by Direct Enzymatic Inhibition and Promoting RET Lysosomal Degradation Independent of Proteasomal Targeting

Iván Plaza-Menacho, Luca Mologni, Elisa Sala et al. · Journal of Biological Chemistry · 2007 · 98 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

RET-Familial Medullary Thyroid Carcinoma Mutants Y791F and S891A Activate a Src/JAK/STAT3 Pathway, Independent of Glial Cell Line–Derived Neurotrophic Factor

Iván Plaza-Menacho, Roelof Koster, Almer M. van der Sloot et al. · Cancer Research · 2005 · 94 citations

Medicine, Genetics, Oncology +17