Iván Plaza-Menacho

A Role for Glial Cell–Derived Neurotrophic Factor–Induced Expression by Inflammatory Cytokines and RET/GFRα1 Receptor Up-regulation in Breast Cancer

Selma Esseghir, Shawn Todd, Toby Hunt et al. · Cancer Research · 2007 · 146 citations · Full text

Tumor Xenografts, Breast Oncology, Cancer Biology +17

Targeting the receptor tyrosine kinase RET sensitizes breast cancer cells to tamoxifen treatment and reveals a role for RET in endocrine resistance

Iván Plaza-Menacho, Andrea Morandi, David Robertson et al. · Oncogene · 2010 · 140 citations

Breast Oncology, Hormonal Receptor, Receptor Tyrosine Kinase +8

GDNF–RET Signaling in ER-Positive Breast Cancers Is a Key Determinant of Response and Resistance to Aromatase Inhibitors

Andrea Morandi, Lesley‐Ann Martin, Qiong Gao et al. · Cancer Research · 2013 · 115 citations · Full text

Sorafenib Functions to Potently Suppress RET Tyrosine Kinase Activity by Direct Enzymatic Inhibition and Promoting RET Lysosomal Degradation Independent of Proteasomal Targeting

Iván Plaza-Menacho, Luca Mologni, Elisa Sala et al. · Journal of Biological Chemistry · 2007 · 97 citations · Full text

RET-Familial Medullary Thyroid Carcinoma Mutants Y791F and S891A Activate a Src/JAK/STAT3 Pathway, Independent of Glial Cell Line–Derived Neurotrophic Factor

Iván Plaza-Menacho, Roelof Koster, Almer M. van der Sloot et al. · Cancer Research · 2005 · 93 citations