Michael J. Chalmers

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

Jang Hyun Choi, Alexander S. Banks, Jennifer L. Estall et al. · Nature · 2010 · 877 citations

Obesity, Metabolic Syndrome, Molecular Pharmacology +8

Molecular Mimicry Regulates ABA Signaling by SnRK2 Kinases and PP2C Phosphatases

Fen-Fen Soon, Ley-Moy Ng, Xiaofeng Zhou et al. · Science · 2011 · 571 citations · Full text

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

Jang Hyun Choi, Alexander S. Banks, Theodore M. Kamenecka et al. · Nature · 2011 · 532 citations · Full text

Molecular Pharmacology, Diabetes Management, Signal Transduction +8

Partial Agonists Activate PPARγ Using a Helix 12 Independent Mechanism

John B. Bruning, Michael J. Chalmers, Swati Prasad et al. · Structure · 2007 · 383 citations · Full text

Molecular Pharmacology, Molecular Physiology, Signal Transduction +7

Probing Protein Ligand Interactions by Automated Hydrogen/Deuterium Exchange Mass Spectrometry

Michael J. Chalmers, Scott A. Busby, Bruce D. Pascal et al. · Analytical Chemistry · 2006 · 305 citations