John B. Bruning

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

Jang Hyun Choi, Alexander S. Banks, Theodore M. Kamenecka et al. · Nature · 2011 · 538 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15

Partial Agonists Activate PPARγ Using a Helix 12 Independent Mechanism

John B. Bruning, Michael J. Chalmers, Swati Prasad et al. · Structure · 2007 · 387 citations · Full text

Medicine, Molecular Biology, Pharmacology +14

Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-δ p66 Subunit and Flap Endonuclease-1

John B. Bruning, Yousif Shamoo · Structure · 2004 · 206 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex

Jun Zhang, Michael J. Chalmers, Keith R. Stayrook et al. · Nature Structural & Molecular Biology · 2011 · 205 citations · Full text

Life Sciences, Biology, Molecular Biology +13

Rare variants in single-minded 1 (SIM1) are associated with severe obesity

Shwetha Ramachandrappa, Anne Raimondo, Anna M. G. Cali et al. · Journal of Clinical Investigation · 2013 · 168 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11