Inhibition of death receptor signals by cellular FLIP

Martin Irmler, Margot Thome, Michael Hahne, +10

Nature

Signal TransductionCell SignalingMedicineApoptosisReceptor (Biochemistry) +6

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

Margot Thome, Pascal Schneider, Kay Hofmann, +11

Nature

MedicineApoptosisPrevent ApoptosisAntiviral ResponseCell Death +4

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

Bente Lowin, Michael Hahne, Chantal Mattmann, +1

Nature

Cytolytic T-cell CytotoxicitySignal TransductionTumor MicroenvironmentFas Lytic PathwaysCell Interaction +10

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

Greta Guarda, Marion Braun, Francesco Staehli, +8

Immunity

InflammationCytokineInflammasome ActivationImmunologyAutoimmunity +2

Differential Expression of NLRP3 among Hematopoietic Cells

Greta Guarda, Manuel Zenger, Amir S. Yazdi, +6

The Journal of Immunology

ImmunologyImmune RegulationPathologyBlood CellEgfp Expression +17

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

Margot Thome, Kay Hofmann, Kim Burns, +4

Current Biology

Signal TransductionMolecular PhysiologySignaling PathwayApoptosisCell Death +8

Characterization of Fas (Apo-1, CD95)-Fas Ligand Interaction

Pascal Schneider, Jean-Luc Bodmer, Nils Holler, +5

Journal of Biological Chemistry

The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis.

Christoph Borner, Isabelle Martinou, Chantal Mattmann, +4

The Journal of Cell Biology

MitophagyApoptosisImmunologyCell DeathMolecular Biology +15

Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter.

Mariusz Zimmer, Robert L. Medcalf, Thomas Fink, +3

Proceedings of the National Academy of Sciences

Elastin PeptidesGeneticsImmunologyProteasomeMolecular Biology +22

NLRC5 Deficiency Selectively Impairs MHC Class I- Dependent Lymphocyte Killing by Cytotoxic T Cells

Francesco Staehli, Kristina Ludigs, Leonhard X. Heinz, +12

The Journal of Immunology