Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease

Christian Griñán‐Ferré, Sandra Codony, Eugènia Pujol, +15

Neurotherapeutics

Soluble Epoxide HydrolaseAlzheimer's DiseaseBiochemistryMedicineDementia +11

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

Júlia Companys‐Alemany, Andreea L. Turcu, Aina Bellver‐Sanchís, +6

Pharmaceutics

Aniline-Based Inhibitors of Influenza H1N1 Virus Acting on Hemagglutinin-Mediated Fusion

Rosana Leiva, Marta Barniol‐Xicota, Sandra Codony, +7

Journal of Medicinal Chemistry

Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency

Mohammad Zarei, Emma Barroso, Rosana Leiva, +12

Diabetes

Pentafluorosulfanyl-containing Triclocarban Analogs with Potent Antimicrobial Activity

Eugènia Pujol, Núria Blanco‐Cabra, Esther Julián, +3

Molecules

Azapropellanes with Anti-Influenza A Virus Activity

Eva Torres, Rosana Leiva, Sabrina Gazzarrini, +5

ACS Medicinal Chemistry Letters

Medicinal ChemistryAmantadine-resistant H1n1 StrainMedicineDrug DiscoveryVirology +10

Mechanism of the Pseudoirreversible Binding of Amantadine to the M2 Proton Channel

Salomé Llabrés, Jordi Juárez‐Jiménez, Matteo Masetti, +6

Journal of the American Chemical Society

Inhibitory ActivityNucleic Acid ChemistryBiochemistryMedicineNatural Sciences +12

11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model

Dolors Puigoriol‐Illamola, Christian Griñán‐Ferré, Foteini Vasilopoulou, +3

Molecular Neurobiology

InflammationSamp8 Mouse ModelCell AutophagyRl-118 Promotes AutophagyImmune Cell Development +8

Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors

Sandra Codony, Elena Valverde, Rosana Leiva, +5

Bioorganic & Medicinal Chemistry

Medicinal ChemistryLipophilic UnitAldehyde DehydrogenaseBiochemistryNatural Sciences +7

2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: <i>In Vivo</i> Evaluation in a Murine Model of Acute Pancreatitis

Sandra Codony, Eugènia Pujol, Javier Pizarro‐Delgado, +16

Journal of Medicinal Chemistry