Concepedia

Otto Kauko

OK

17

Publications

933

Citations

13

H-Index

2007

Active since

Affiliations

University of Turku(Current)

Åbo Akademi University

University of Helsinki

Turku Centre for Biotechnology

Institute for Molecular Medicine Finland

Otto Kauko is an author at University of Turku specializing in medicine, cell biology, and tumor biology.

Top concepts

MedicineCell BiologyTumor BiologyCancer BiologyCell SignalingSignal TransductionCancer ResearchSystems BiologyEngineeringPharmacology

Publications per year

2007–2023

17

Publications

17

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin et al. · Cell · 2021 · 208 citations · Full text

Cancer Research, Signal Transduction, Signaling Pathway +9

PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells

Otto Kauko, Caitlin M. O’Connor, Evgeny Kulesskiy et al. · Science Translational Medicine · 2018 · 152 citations · Full text

Cell Signaling, Medicine, Receptor Tyrosine Kinase +13

Oncoprotein <scp>CIP</scp> 2A is stabilized via interaction with tumor suppressor <scp>PP</scp> 2A/B56

Jiao Wang, Juha Okkeri, Karolina Pavic et al. · EMBO Reports · 2017 · 101 citations · Full text

Signal Transduction, Cell Regulation, Oncogenic Agent +7

CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes

Mika Niemelä, Otto Kauko, Harri Sihto et al. · Oncogene · 2012 · 82 citations · Full text

Breast Oncology, Oncology, Cip2a-regulated Phenotypes +11

Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1

Otto Kauko, Susumu Y. Imanishi, Evgeny Kulesskiy et al. · Journal of Biological Chemistry · 2020 · 71 citations · Full text

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