Concepedia

Caitlin M. O’Connor

CM

Statistics

Publications

15

Citations

855

H-Index

15

Active since

2009

Affiliations

Case Western Reserve University(Current)

University of Michigan

Michigan Medicine

Icahn School of Medicine at Mount Sinai

University School

Caitlin M. O’Connor is an author at Case Western Reserve University specializing in oncology, protein phosphatase 2a regulation, and life sciences.

Publications per year

2009–2024

15

Publications

15

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

Jaya Sangodkar, Abbey Perl, Rita Tohmé et al. · Journal of Clinical Investigation · 2017 · 199 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Selective PP2A Enhancement through Biased Heterotrimer Stabilization

Daniel Léonard, Wei Huang, Sudeh Izadmehr et al. · Cell · 2020 · 178 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells

Otto Kauko, Caitlin M. O’Connor, Evgeny Kulesskiy et al. · Science Translational Medicine · 2018 · 157 citations · Full text

Medicine, Oncology, Pharmacology +17

The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis

Sarah E. Taylor, Caitlin M. O’Connor, Zhizhi Wang et al. · Cancer Research · 2019 · 60 citations · Full text

Medicine, Cancer Biology, Oncology +9

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

Caitlin M. O’Connor, Daniel Léonard, Danica Wiredja et al. · Oncogene · 2019 · 48 citations · Full text

Medicine, Cell Biology, Pharmacology +14

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