Concepedia

Caitlin M. O’Connor

CM

15

Publications

826

Citations

14

H-Index

2009

Active since

Affiliations

Case Western Reserve University(Current)

University of Michigan

Icahn School of Medicine at Mount Sinai

University School

University of Virginia

Caitlin M. O’Connor is an author at Case Western Reserve University specializing in medicine, cell biology, and cell signaling.

ORCID

Top concepts

Publications per year

2009–2024

15

Publications

15

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

Jaya Sangodkar, Abbey Perl, Rita Tohmé et al. · Journal of Clinical Investigation · 2017 · 196 citations · Full text

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Selective PP2A Enhancement through Biased Heterotrimer Stabilization

Daniel Léonard, Wei Huang, Sudeh Izadmehr et al. · Cell · 2020 · 174 citations · Full text

PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells

Otto Kauko, Caitlin M. O’Connor, Evgeny Kulesskiy et al. · Science Translational Medicine · 2018 · 152 citations · Full text

, , +13

The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis

Sarah E. Taylor, Caitlin M. O’Connor, Zhizhi Wang et al. · Cancer Research · 2019 · 58 citations · Full text

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

Caitlin M. O’Connor, Daniel Léonard, Danica Wiredja et al. · Oncogene · 2019 · 46 citations · Full text

, , +10

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