Jiang‐Fan Chen

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

Silvia Deaglio, Karen M. Dwyer, Wenda Gao et al. · The Journal of Experimental Medicine · 2007 · 2.3K citations · Full text

A2A adenosine receptor protects tumors from antitumor T cells

Akio Ohta, Elieser Gorelik, Simon J. Prasad et al. · Proceedings of the National Academy of Sciences · 2006 · 1K citations · Full text

Cancer Immunosurveillance, Medicine, Tumor Growth +12

Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture

Nanna Goldman, Michael Chen, Takumi Fujita et al. · Nature Neuroscience · 2010 · 791 citations · Full text

Pain Research, Pain Medicine, Medicine +6

Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

Zhi‐Li Huang, Wei‐Min Qu, Naomi Eguchi et al. · Nature Neuroscience · 2005 · 624 citations

Molecular Pharmacology, Neurophysiology, Medicine +9

A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice.

Jiang‐Fan Chen, Zhihong Huang, Jianya Ma et al. · PubMed · 1999 · 531 citations · Full text

Transient Focal Ischemia, Social Sciences, Cerebral Vascular Regulation +19