Michelle Simons

Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes

Craig D. Hughes, Hong Wang, Harshad Ghodke et al. · Nucleic Acids Research · 2013 · 54 citations · Full text

Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers

Michelle Simons, Svetlana Gretton, Gary Silkstone et al. · Bioscience Reports · 2018 · 38 citations · Full text

Hemoglobin-based Oxygen Carriers, Redox Biology, Oxidative Stress +17

Engineering tyrosine electron transfer pathways decreases oxidative toxicity in hemoglobin: implications for blood substitute design

Gary Silkstone, Rebecca S. Silkstone, Michael T. Wilson et al. · Biochemical Journal · 2016 · 32 citations · Full text

Redox-active Tyrosine Mutation, Engineering, Iron Metabolism +18

Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute

Chris E. Cooper, Gary Silkstone, Michelle Simons et al. · Free Radical Biology and Medicine · 2018 · 26 citations · Full text

Iron Metabolism, Molecular Biology, β Subunits +16

Recruitment of UvrBC complexes to UV-induced damage in the absence of UvrA increases cell survival

Luke Springall, Craig D. Hughes, Michelle Simons et al. · Nucleic Acids Research · 2017 · 21 citations · Full text

Ultraviolet Light, Dna Damage, Bacterial Ner +20