Craig D. Hughes

Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms

Suman De, David C. Wirthensohn, Patrick Flagmeier et al. · Nature Communications · 2019 · 446 citations · Full text

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Plamena R. Angelova, Minee L. Choi, Alexey V. Berezhnov et al. · Cell Death and Differentiation · 2020 · 284 citations · Full text

Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis

Craig D. Hughes, Minee L. Choi, Mina Ryten et al. · Acta Neuropathologica · 2018 · 163 citations · Full text

Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death

Craig D. Hughes, Minee L. Choi, Jee Hyun Yi et al. · Communications Biology · 2020 · 101 citations · Full text

Longitudinal tracking of 97 esophageal adenocarcinomas using liquid biopsy sampling

E. Ococks, Alexander M. Frankell, N. Masque Soler et al. · Annals of Oncology · 2021 · 101 citations · Full text