Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a []GTPγS binding study

Adrian Newman‐Tancredi, Samantha Gavaudan, Caroline Conte, +5

European Journal of Pharmacology

Molecular PharmacologyAntagonist ActionsAntipsychotic AgentsPsychiatryMedicine +6

Actions of α2 adrenoceptor ligands at α2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for α2A adrenoceptors

Adrian Newman‐Tancredi, Jean‐Paul Nicolas, Valérie Audinot, +6

Naunyn-Schmiedeberg s Archives of Pharmacology

Molecular PharmacologyMedicineα2 AdrenoceptorPhysiology5-Ht1a Receptors +6

Clozapine is a partial agonist at cloned, human serotonin 5-HT1A receptors

Adrian Newman‐Tancredi, C. Chaput, Laurence Verrièle, +1

Neuropharmacology

Psychoactive DrugFunctional SelectivityMedicineSchizophreniaNeuroscience +3

Agonist and Inverse Agonist Efficacy at Human Recombinant Serotonin 5-HT 1A Receptors as a Function of Receptor:G-protein Stoichiometry

Adrian Newman‐Tancredi, Caroline Conte, C. Chaput, +2

Neuropharmacology

Signal TransductionFunctional SelectivityMedicineG Protein-coupled ReceptorPhysiology +7

Inhibition of the constitutive activity of human 5‐HT_1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635

Adrian Newman‐Tancredi, Caroline Conte, C. Chaput, +2

British Journal of Pharmacology

Molecular PharmacologyWay 100,635Spiperone-induced InhibitionBiochemistryFunctional Selectivity +13

[35S]Guanosine-5′-O-(3-thio)triphosphate Binding as a Measure of Efficacy at Human Recombinant Dopamine D4.4Receptors: Actions of Antiparkinsonian and Antipsychotic Agents

Adrian Newman‐Tancredi, Valérie Audinot, C. Chaput, +2

Journal of Pharmacology and Experimental Therapeutics

Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy

Adrian Newman‐Tancredi, Caroline Conte, C. Chaput, +5

Naunyn-Schmiedeberg s Archives of Pharmacology

Antimigraine DrugsFunctional SelectivityAgonist ActivityPharmacologyAcute Therapy +4

S 15535 and WAY 100,635 antagonise 5-HT-stimulated [35S]GTPγS binding at cloned human 5-HT1A receptors

Adrian Newman‐Tancredi, C. Chaput, Laurence Verrièle, +1

European Journal of Pharmacology

Way 100,635Molecular PhysiologySignal TransductionG Protein-coupled ReceptorImmunology +5

Actions of novel agonists, antagonists and antipsychotic agents at recombinant rat 5-HT6 receptors: A comparative study of coupling to Gαs

Delphine S. Dupuis, Clotilde Mannoury la Cour, C. Chaput, +3

European Journal of Pharmacology

Molecular PharmacologyAntipsychotic AgentsPsychiatryFunctional SelectivityMedicine +9

Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: Definition of its binding profile using agonists, antagonists and inverse agonists

Adrian Newman‐Tancredi, Laurence Verrièle, C. Chaput, +1

Naunyn-Schmiedeberg s Archives of Pharmacology

Selective RadioligandBiochemistryFunctional SelectivityMedicineNative Rat +9