Concepedia

Author

R. Brundiers

Max Planck Institute for Biophysical Chemistry

Also Known As

R. Brundiers, Ralf Brundiers

14

Publications

453

Citations

9

H-Index

19

Concepts

All Affiliations

Max Planck Institute for Biophysical ChemistryMax Planck SocietyMax Planck Institute of Molecular PhysiologyMax Planck Institute for Medical ResearchMorphoSys (Germany)
RB

About

R. Brundiers is an author at Max Planck Institute for Biophysical Chemistry specializing in signal transduction, medicine, and cell signaling.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

4

4

203

2

Biochemistry

3

3

167

3

Natural Sciences

2

2

115

4

Cell Biology

2

2

46

5

Cellular Physiology

1

1

36

R. Brundiers

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8

Publications

436

Citations

8

H-Index

YearCitations

Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate

Nils Ostermann, Ilme Schlichting, R. Brundiers,

Structure

2000

105

Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by <i>Escherichia coli</i> thymidylate kinase

Arnon Lavie, Nils Ostermann, R. Brundiers,

Proceedings of the National Academy of Sciences

1998

90

Crystal Structure of Yeast Thymidylate Kinase Complexed with the Bisubstrate Inhibitor <i>P</i><sup>1</sup>-(5‘-Adenosyl) <i>P</i><sup>5</sup>-(5‘-Thymidyl) Pentaphosphate (TP<sub>5</sub>A) at 2.0 Å Resolution:  Implications for Catalysis and AZT Activation<sup>,</sup>

Arnon Lavie, Manfred Konrad, R. Brundiers,

Biochemistry

1998

70

Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation

R. Brundiers, Arnon Lavie, T. Veit,

Journal of Biological Chemistry

1999

63

Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants’ improved kinetics with the HIV prodrug metabolite AZTMP 1 1Edited by J. Karn

Nils Ostermann, Arnon Lavie, S. Padiyar,

Journal of Molecular Biology

2000

52

Kirrel2, a novel immunoglobulin superfamily gene expressed primarily in β cells of the pancreatic islets☆

Chao Sun, Daniel Kilburn, Alex Lukashin,

Genomics

2003

36

A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

Angelika Oehmig, Andrea Klotzbücher, Maria Thomas,

BMC Genomics

2008

10

Expressing engineered thymidylate kinase variants in human cells to improve AZT phosphorylation and human immunodeficiency virus inhibition

Birgitta M. Wöhrl, Laurence Loubière, R. Brundiers,

Journal of General Virology

2005

10

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