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Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants’ improved kinetics with the HIV prodrug metabolite AZTMP 1 1Edited by J. Karn

Molecular PharmacologySignal TransductionBiochemistryAzt ActivationMedicineJ. KarnHuman RetrovirusAntiviral Drug DevelopmentAntiviral ResponseAntiviral DrugHivPharmacologyCell SignalingDrug Discovery