Nigel M. Stapleton

Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

Nigel M. Stapleton, Jan Terje Andersen, Annette M. Stemerding et al. · Nature Communications · 2011 · 274 citations · Full text

FcRn: an IgG receptor on phagocytes with a novel role in phagocytosis

Gestur Vidarsson, Annette M. Stemerding, Nigel M. Stapleton et al. · Blood · 2006 · 188 citations · Full text

On the Perplexingly Low Rate of Transport of IgG2 across the Human Placenta

H Einarsdottir, Nigel M. Stapleton, Sicco A. Scherjon et al. · PLoS ONE · 2014 · 37 citations · Full text

Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge

Nigel M. Stapleton, Maximilian Brinkhaus, Kathryn L. Armour et al. · Scientific Reports · 2019 · 33 citations · Full text

Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport

Nigel M. Stapleton, Sylvia Armstrong‐Fisher, Jan Terje Andersen et al. · Molecular Immunology · 2018 · 18 citations · Full text