Su Yang

CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington’s disease

Su Yang, Renbao Chang, Huiming Yang et al. · Journal of Clinical Investigation · 2017 · 382 citations · Full text

Genetics, Polyglutamine Repeat, Molecular Biology +17

A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease

Sen Yan, Zhuchi Tu, Zhaoming Liu et al. · Cell · 2018 · 330 citations

Knockout Mouse, Neurodegenerative Diseases, Neurobiology Of Disease +13

SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models

Axel Hyrenius‐Wittsten, Su Yang, Minhee Park et al. · Science Translational Medicine · 2021 · 223 citations · Full text

Tumor Innervation, Immunology, Immunoediting +17

Dual sgRNAs facilitate CRISPR/Cas9‐mediated mouse genome targeting

Jiankui Zhou, Jianying Wang, Bin Shen et al. · FEBS Journal · 2014 · 152 citations · Full text

Dual Sgrnas, Systems Biology, Off-target Effect +11

Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos

Zhuchi Tu, Weili Yang, Sen Yan et al. · Scientific Reports · 2017 · 132 citations · Full text