Falu Wang

Asymmetric Total Syntheses of <i>Kopsia</i> Indole Alkaloids

Lingying Leng, Xiaohan Zhou, Qi Liao et al. · Angewandte Chemie International Edition · 2017 · 101 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron

Baoxue Quan, Huiping Shuai, Anjie Xia et al. · Nature Microbiology · 2022 · 101 citations · Full text

Medicine, Infectious Diseases, Pharmacology +8

Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor

Yueshan Li, Liting Zhang, Yifei Wang et al. · Nature Communications · 2022 · 98 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

A new generation Mpro inhibitor with potent activity against SARS-CoV-2 Omicron variants

Chong Huang, Huiping Shuai, Jingxin Qiao et al. · Signal Transduction and Targeted Therapy · 2023 · 81 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +15

Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis

Jiao Yan, Jinshan Nan, Bo Mu et al. · European Journal of Medicinal Chemistry · 2022 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12