Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model

Wen Yuan, Chun‐Ting Wang, Tian‐Tai Ma, +6

Cancer Science

Silencing of <i>pkm2</i> increases the efficacy of docetaxel in human lung cancer xenografts in mice

Dan Li, Jing Zhang, Yongsheng Wang, +8

Cancer Science

PathologyCancer BiologyTumor BiologyCancer Cell BiologyPulmonary Pharmacology +14

Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis

Jiao Yan, Jinshan Nan, Bo Mu, +3

European Journal of Medicinal Chemistry

Anti-inflammatoryNovel TherapyPotent InhibitorMedicineDrug Discovery +10

Non-classical ferroptosis inhibition by a small molecule targeting PHB2

Wei Yang, Bo Mu, Jing You, +13

Nature Communications

SATB1 plays an oncogenic role in esophageal cancer by up-regulation of FN1 and PDGFRB

Guiqin Song, Kang Liu, Xiaolin Yang, +8

Oncotarget

Development of novel in silico prediction model for drug-induced ototoxicity by using naïve Bayes classifier approach

Hui Zhang, Chun‐Tao Liu, Jun Mao, +3

Toxicology in Vitro

Pharmacokinetic ModelingPredictive ToxicologyDrug DiscoveryPharmacologyBiostatistics +6

Quercetin Liposome Sensitizes Colon Carcinoma to Thermotherapy and Thermochemotherapy in Mice Models

Bing He, Xin Wang, Wenjing Xiao, +5

Integrative Cancer Therapies

OncologyChemoprevention StrategyMedicineImmunologySoluble Quercetin Liposome +10

Structural Optimization and Structure–Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6<i>H</i>-pyrimido[5,4-<i>b</i>][1,4]oxazin-7(8<i>H</i>)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants

Shulei Pan, Liting Zhang, Xinling Luo, +13

Journal of Medicinal Chemistry

Discovery of a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase: Structural activity relationship and antitumor activity both in vitro and in vivo

Huachao Bin, Pei Chen, Ming Wu, +9

European Journal of Medicinal Chemistry

Antitumor ActivitySignaling PathwayStructural Activity RelationshipCell DeathAtaxia Telangiectasia +6

The Effects and Mechanisms by which Saikosaponin-D Enhances the Sensitivity of Human Non-small Cell Lung Cancer Cells to Gefitinib

Jiancai Tang, Feng Long, Jia Zhao, +4

Journal of Cancer

ImmunologyDown-regulated Stat3Cancer BiologyTumor BiologyOncology +14