Concepedia
Statistics
Publications
5
Citations
329
H-Index
Active since
2007
Affiliations
University of Chicago(Current)
Johns Hopkins University
Melissa A. Mefford is an author at University of Chicago specializing in molecular biology, chromatin, and gene expression.
Top concepts
Molecular BiologyGeneticsMedicineChromatinRna BiologyGene ExpressionNatural SciencesMolecular GeneticsRna SplicingDna Replication
Publications per year
2007–2015
U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing
Angela K. Hilliker, Melissa A. Mefford, Jonathan P. Staley · Genes & Development · 2007 · 110 citations · Full text
Evidence for a group II intron–like catalytic triplex in the spliceosome
Sebastian M. Fica, Melissa A. Mefford, Joseph A. Piccirilli et al. · Nature Structural & Molecular Biology · 2014 · 109 citations · Full text
Group Ii, Molecular Biology, Molecular Genetics +4
Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps
Melissa A. Mefford, Jonathan P. Staley · RNA · 2009 · 79 citations · Full text
Splice Site Cleavage, Genetics, Rna Splicing +18
RNA connectivity requirements between conserved elements in the core of the yeast telomerase RNP
Melissa A. Mefford, Qundeel Rafiq, David C. Zappulla · The EMBO Journal · 2013 · 20 citations · Full text
Chromatin, Yeast Telomerase Rnp, Conserved Elements +10
Physical Connectivity Mapping by Circular Permutation of Human Telomerase RNA Reveals New Regions Critical for Activity and Processivity
Melissa A. Mefford, David C. Zappulla · Molecular and Cellular Biology · 2015 · 11 citations · Full text
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