Concepedia

Sebastian M. Fica

SM

14

Publications

1.4K

Citations

12

H-Index

2013

Active since

Affiliations

MRC Laboratory of Molecular Biology(Current)

University of Oxford

University College London

University of Chicago

National Hospital for Neurology and Neurosurgery

Sebastian M. Fica is an author at MRC Laboratory of Molecular Biology specializing in molecular biology, natural sciences, and structural biology.

Top concepts

Molecular BiologyNatural SciencesGeneticsMedicineRna SplicingMolecular GeneticsStructural BiologyBiomolecular EngineeringTranscriptional RegulationBiology

Publications per year

2013–2024

14

Publications

14

RNA catalyses nuclear pre-mRNA splicing

Sebastian M. Fica, Nicole Tuttle, Thaddeus J. Novak et al. · Nature · 2013 · 333 citations · Full text

Transcriptional Regulation, Natural Sciences, Genetics +9

Cryo-EM structure of the spliceosome immediately after branching

Wojciech P. Galej, Max E. Wilkinson, Sebastian M. Fica et al. · Nature · 2016 · 242 citations · Full text

Molecular Biology, Cellular Structure, Cryo-em Structure +2

Structure of a spliceosome remodelled for exon ligation

Sebastian M. Fica, Chris Oubridge, Wojciech P. Galej et al. · Nature · 2017 · 183 citations

Exon Ligation, Molecular Biology, Splicing Variant +2

Postcatalytic spliceosome structure reveals mechanism of 3′–splice site selection

Max E. Wilkinson, Sebastian M. Fica, Wojciech P. Galej et al. · Science · 2017 · 131 citations · Full text

A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation

Sebastian M. Fica, Chris Oubridge, Max E. Wilkinson et al. · Science · 2019 · 126 citations · Full text

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