Hongyang Xu

AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach, Denzil Bernard, Kong T. Nguyen et al. · Scientific Reports · 2024 · 120 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +16

Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia

Hongyang Xu, Rojina Ranjit, Arlan Richardson et al. · Journal of Cachexia Sarcopenia and Muscle · 2021 · 80 citations · Full text

Life Sciences, Biochemistry, Physiology +12

Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice

Rizwan Qaisar, Gavin Pharaoh, Shylesh Bhaskaran et al. · International Journal of Molecular Sciences · 2020 · 53 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Elevated phospholipid hydroperoxide glutathione peroxidase (GPX4) expression modulates oxylipin formation and inhibits age-related skeletal muscle atrophy and weakness

Agnieszka Czyżowska, Jacob L. Brown, Hongyang Xu et al. · Redox Biology · 2023 · 53 citations · Full text

Medicine, Biochemistry, Physiology +17

Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia

Bumsoo Ahn, Rojina Ranjit, Parker Kneis et al. · Aging Cell · 2022 · 51 citations · Full text

Life Sciences, Cell Biology, Physiology +17