Marianne Möller

PCSK9 LNA Antisense Oligonucleotides Induce Sustained Reduction of LDL Cholesterol in Nonhuman Primates

Marie Lindholm, Joacim Elmén, Niels Fisker et al. · Molecular Therapy · 2011 · 145 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Hepatotoxic Potential of Therapeutic Oligonucleotides Can Be Predicted from Their Sequence and Modification Pattern

Peter Hagedorn, Victor Yakimov, Søren Ottosen et al. · Nucleic Acid Therapeutics · 2013 · 97 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice

Peter Hagedorn, Malene Pontoppidan, Tina S Bisgaard et al. · Nucleic Acids Research · 2018 · 71 citations · Full text

Life Sciences, Molecular Biology, Gene Expression +12

Cytotoxic versus genotoxic effects of nitric oxide (NO)

Helga Stopper, Marianne Möller, Heike Bömmel et al. · Toxicology Letters · 1999 · 21 citations

Pharmacy, Toxicology, Apoptosis +13

In vitro and in vivo properties of therapeutic oligonucleotides containing non-chiral 3′ and 5′ thiophosphate linkages

Jörg Duschmalé, Henrik F. Hansen, Martina Duschmalé et al. · Nucleic Acids Research · 2019 · 21 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +17