Donald H. Guthrie

The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles

Geoffrey B. Varty, Mariagrazia Grilli, A Forlani et al. · Psychopharmacology · 2005 · 166 citations

Medicine, Neuroscience, Pharmacology +16

Characterization of the nociceptin receptor (ORL-1) agonist, Ro64-6198, in tests of anxiety across multiple species

Geoffrey B. Varty, Lynn A. Hyde, Robert A. Hodgson et al. · Psychopharmacology · 2005 · 84 citations

Medicine, Neuroscience, Pharmacology +14

Comparison of the V1b antagonist, SSR149415, and the CRF1 antagonist, CP-154,526, in rodent models of anxiety and depression

Robert A. Hodgson, Guy A. Higgins, Donald H. Guthrie et al. · Pharmacology Biochemistry and Behavior · 2007 · 78 citations

Medicine, Neuroscience, Pharmacology +13

The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octane-3-carboxamide (SCH 655842): Comparison of efficacy and side effects across rodent species

Sherry Lu, Guy A. Higgins, Robert A. Hodgson et al. · European Journal of Pharmacology · 2011 · 23 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination

Robert A. Hodgson, Lynn A. Hyde, Donald H. Guthrie et al. · Pharmacology Biochemistry and Behavior · 2010 · 15 citations

Life Sciences, Neuroscience, Pharmacology +12