Concepedia

The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octane-3-carboxamide (SCH 655842): Comparison of efficacy and side effects across rodent species

Sherry Lu, Guy A. Higgins, Robert A. Hodgson, Lynn A. Hyde, Robert A. Del Vecchio, Donald H. Guthrie, Tatiana M. Kazdoba, Martha F. McCool, Cynthia A. Morgan, Ana Bercovici,

European Journal of Pharmacology · 2011 · 23 citations · 25 references

DOI

Concepts

References

25

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

Jean‐Claude Meunier, Catherine Mollereau, Lawrence Toll et al. · Nature · 1995 · 1.9K citations

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Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor

Rainer K. Reinscheid, Hans‐Peter Nothacker, Anne Bourson et al. · Science · 1995 · 1.8K citations

, , +17

ORL1, a novel member of the opioid receptor family

Catherine Mollereau, Marc Parmentier, Pierre Mailleux et al. · FEBS Letters · 1994 · 1.1K citations

, , +17

Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress

François Jenck, Jean‐Luc Moreau, James R. Martin et al. · Proceedings of the National Academy of Sciences · 1997 · 348 citations

, , +15

A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: Anxiolytic profile in the rat

François Jenck, Juergen Wichmann, Frank M. Dautzenberg et al. · Proceedings of the National Academy of Sciences · 2000 · 274 citations

, , +14