Manjiong Wang

Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer’s Disease

Fei Mao, Huan Wang, Wei Ni et al. · ACS Chemical Neuroscience · 2017 · 63 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

A novel multistage antiplasmodial inhibitor targeting Plasmodium falciparum histone deacetylase 1

Zhenghui Huang, Ruoxi Li, Tongke Tang et al. · Cell Discovery · 2020 · 56 citations · Full text

Medicine, Molecular Biology, Pharmacology +13

Drug repositioning by prediction of drug’s anatomical therapeutic chemical code via network-based inference approaches

Yayuan Peng, Manjiong Wang, Yixiang Xu et al. · Briefings in Bioinformatics · 2020 · 47 citations

Life Sciences, Pharmacology, Drug Design +13

Discovery of Novel <i>Plasmodium falciparum</i> HDAC1 Inhibitors with Dual-Stage Antimalarial Potency and Improved Safety Based on the Clinical Anticancer Drug Candidate Quisinostat

Ruoxi Li, Dazheng Ling, Tongke Tang et al. · Journal of Medicinal Chemistry · 2021 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Drug Repurposing of Quisinostat to Discover Novel <i>Plasmodium falciparum</i> HDAC1 Inhibitors with Enhanced Triple-Stage Antimalarial Activity and Improved Safety

Manjiong Wang, Tongke Tang, Ruoxi Li et al. · Journal of Medicinal Chemistry · 2022 · 33 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17