Philip A. MacFaul

Matched Molecular Pairs as a Guide in the Optimization of Pharmaceutical Properties; a Study of Aqueous Solubility, Plasma Protein Binding and Oral Exposure

Andrew G. Leach, Huw Jones, David A. Cosgrove et al. · Journal of Medicinal Chemistry · 2006 · 283 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

A Radical Account of “Oxygenated Fenton Chemistry” ¹

Philip A. MacFaul, D. D. M. Wayner, K. U. Ingold · Accounts of Chemical Research · 1998 · 195 citations · Full text

Natural Sciences, Chemistry, Analytical Chemistry +11

AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and <i>ESR1</i> -Mutant Breast Tumors in Preclinical Models

Hazel M. Weir, Robert H. Bradbury, Mandy Lawson et al. · Cancer Research · 2016 · 174 citations

Medicine, Oncology, Pharmacology +16

A Putative Monooxygenase Mimic Which Functions via Well-Disguised Free Radical Chemistry¹

Philip A. MacFaul, K. U. Ingold, D. D. M. Wayner et al. · Journal of the American Chemical Society · 1997 · 171 citations

Natural Sciences, Biochemistry, Chemistry +10

The Titanium(<scp>IV</scp>)‐Catalyzed Epoxidation of Alkenes by <i>tert</i>‐Alkyl Hydroperoxides

Richard D. Oldroyd, John Meurig Thomas, Thomas Maschmeyer et al. · Angewandte Chemie International Edition in English · 1996 · 168 citations

Natural Sciences, Chemistry, Materials Science +14