Rhonda S. Wood

Design, Parallel Synthesis, and Crystal Structures of Pyrazinone Antithrombotics as Selective Inhibitors of the Tissue Factor VIIa Complex

John J. Parlow, Brenda L. Case, Thomas A. Dice et al. · Journal of Medicinal Chemistry · 2003 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pharmacological Interruption of Acute Thrombus Formation with Minimal Hemorrhagic Complications by a Small Molecule Tissue Factor/Factor VIIa Inhibitor: Comparison to Factor Xa and Thrombin Inhibition in a Nonhuman Primate Thrombosis Model

Osman D. Suleymanov, James A. Szalony, Anita K. Salyers et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 64 citations

Medicine, Hematology, Pharmacology +16

Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex

Michael S. South, Brenda L. Case, Rhonda S. Wood et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Administration of a small molecule tissue factor/Factor VIIa inhibitor in a non-human primate thrombosis model of venous thrombosis: effects on thrombus formation and bleeding time

James A. Szalony, Osman D. Suleymanov, Anita K. Salyers et al. · Thrombosis Research · 2003 · 37 citations

Medicine, Pharmacokinetics, Pharmacology +17

Assessment of Bleeding Propensity in Non-Human Primates by Combination of Selective Tissue Factor/VIIa Inhibition and Aspirin Compared to Warfarin and Aspirin Treatment

Anita K. Salyers, James A. Szalony, Osman D. Suleymanov et al. · Pharmacology · 2003 · 15 citations

Medicine, Hematology, Pharmacology +17